Squaresoft was pure gold back in the day. S-E is still pretty good with their most important games, but their not so big titles usually end up being pretty bad.
Level 5 is probably my current favorite company, they have not made a bad game yet.
Team Ico is excellent for their ability to make games that are pure art.
Nintendo is good at making killer apps, even if they are few and far apart.
Capcom is great at making action games that really keep you on your toes (DMC, RE)
Epic makes some of the best FPS ever.
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